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The AFC North winner will host the surging Texans, while the Broncos, the top seed, will sit as the Chargers travel to the Patriots. The Bills will travel to the red-hot Jacksonville Jaguars.
The NFL's playoff bracket will be finalized Sunday. Here's what it currently looks like and what the wild-card matchups will be.
NFL Network's Kurt Warner previews the matchup of quarterbacks between the Buffalo Bills' Josh Allen and the Jacksonville Jaguars' Trevor Lawrence ahead of the AFC Wild Card game.
Get the latest NFL playoff picture and bracket ahead of the Week 18 slate.
The Houston Texans play their third-consecutive Wild Card game - see what bold predictions we make ahead of their tilt with the Steelers.
The 1980 Raiders became the first wild card team to hoist the Lombardi Trophy after disbanding the favored Eagles in Super Bowl XV. It would be another 17 years before another wild card team, the Broncos, won the Super Bowl after defeating the Packers in one of the biggest upsets in NFL history.