While current clinical trials for cardiac regeneration using induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) ...

Transplantation of organs or tissues between genetically nonidentical individuals of the same species (and different species) is plagued by rejection and its associated problems. "Foreignness" is ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

Current treatments to prevent organ transplant rejection focus mainly on suppressing T cells, part of the adaptive immune system. However, the innate immune system—the body’s first line of defense ...

Transplant rejection occurs when the recipient’s immune system attacks the transplanted organ. This can cause the transplanted organ to fail, undermining the purpose of the transplant and leading to a ...

Panels designed to identify acute cellular rejection, antibody-mediated rejection without ...

5,000-participant, multi-center registry supported by iMDx’s central lab and transplant center partners New hospital-based data seeks to further differentiate pending kitted assay that measures ...

Following a heart transplant, patients must undergo surgical biopsies so that clinicians can monitor for signs of organ rejection. A new study shows the promise of a biomarker that could allow doctors ...