Biomolecular condensates were long believed to be simple liquid blobs inside cells. Researchers have now uncovered that some are actually supported by fine protein filaments forming an internal ...
A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...
The first engineered cell therapy has come to the fight against solid tumors. Fox Chase Cancer Center has begun using Tecelra, an FDA-approved treatment for synovial sarcoma.
A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...
Northwestern researchers have shown that when it comes to cancer vaccines, arrangement can be just as important as ingredients. By repositioning a small fragment of an HPV protein on a DNA-based ...
Explore how HPV tumours are targeted by innovative vaccine designs that enhance immune response against cancer effectively.
Throughout the past decade, Northwestern University scientists have uncovered a striking principle of vaccine design: Performance depends not only on vaccine components but also on vaccine structure.
DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...
Thanks to modern therapies, a cancer diagnosis is no longer an automatic death sentence. But many patients still suffer from ...
Scientists have identified a hidden barrier that prevents immunotherapy from working against a rare liver cancer. Immunotherapy, which activates the body’s own immune system to kill cancer cells, has ...
Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes. These droplet-like dynamic assemblies control the way in which DNA is turned into ...