Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that require surgery in the first months of life. For decades, scientists have ...

After decades of mystery, researchers at Gladstone Institutes identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice. SAN FRANCISCO—October 22, ...

Three copies of chromosome 21 cause Down syndrome (DS), and roughly half of children born each year in the United States with DS—approximately 2,600—also have congenital heart defects (CHDs).

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs). What is ...

AURORA, Colo. (Sept. 24, 2025) – In a groundbreaking new study published in Nature Communications, researchers from the Linda Crnic Institute for Down Syndrome (Crnic Institute) at the University of ...