Jessica Nance, MD, MS, discusses the significance of surrogate end points, like functional assessments, in clinical trials of treatments for Duchenne muscular dystrophy and their implications for ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

The U.S. Social Security Administration has requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to (1) provide an overview of ways to collect information about ...

Operationally define challenging behaviors. Challenging behaviors should be defined in terms that are specific, observable, and measureable (i.e., one can see and count the behaviors). Be specific ...

Objectives: To examine (a) return to competitive sport within 12 months of anterior cruciate ligament (ACL) reconstruction, (b) maintenance of competitive participation at follow up, and (c) the ...