A hybrid method that combines Laplace's approximation and Monte Carlo simulations to evaluate integrals in the likelihood function is proposed for estimation of the parameters in nonlinear mixed ...

Keywords: Statistical analyses. Regression models. Post-earthquake ignitions. Data analyses. California. Ground shaking. Generalized linear mixed models. Goodness-of ...

Response-adaptive designs are important alternatives to equal allocation in clinical trials because equal treatment allocation has been found to have ethical issues. In this article we discuss the ...