Microvillus inclusion disease (MVID) is a cause of chronic watery diarrhea that is attributed to a lack of nutrient absorption in the gastrointestinal tract in newborns. The disease can lead to ...
Intestinal microvilli, finger-like protrusions on the cell surface, are packed with the motor protein myosin-1a. This myosin was thought to serve a purely structural role, but now Vanderbilt cell ...
The major protein associated with actin in the microfilament core of intestinal microvilli has been purified. This protein, for which we propose the name villin, has a polypeptide molecular weight of ...
Crofelemer previously granted Orphan Drug Designation by the FDA and the EMA for both short bowel syndrome and microvillus inclusion disease Due to the very low incidence and prevalence of cholera in ...
Jaguar expects first results in Q2 2025 of proof-of-concept investigator-initiated trials of crofelemer for the rare diseases short bowel syndrome with intestinal failure and microvillus inclusion ...
In mice, deletion of the Rab8 protein disrupts organized molecular distribution to membranes of intestinal epithelial cells. Death by starvation follows, exactly as it does in humans with microvillus ...
SAN FRANCISCO, CALIFORNIA / ACCESS Newswire / November 20, 2025 / Jaguar Health, Inc. (NASDAQ:JAGX) (Jaguar) family company Napo Pharmaceuticals (Napo) today announced that, in support of a possible ...
Matthew Tyska, Ph.D., recalls being intrigued, from the first day of his postdoctoral fellowship in 1999, with a nearly 30-year-old photograph. It was an electron micrograph that showed the internal ...
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