In atherosclerosis(AS), plaque rupture or detachment is a major cause of severe cardiovascular events, while plaque stability is influenced by multiple pathological factors, such as abnormal collagen ...

For decades, Americans have been advised that cutting fat was key for a heart-healthy diet, spurring an industry of low-fat dairy products. A new generation of ...

Scientists have successfully restored hearing in animal models of ENPP1 deficiency, a genetic disease in which individuals lack an enzyme essential for bone and blood vessel health. The rare disorder ...

Potent, selective ABCC6-targeting positive functional modulator (PFM) improved multiple markers of renal function in animal models of chronic kidney disease (CKD) PFM improved inorganic pyrophosphate ...

BOSTON, Oct. 10, 2023 (GLOBE NEWSWIRE) -- Inozyme Pharma, Inc. (INZY) (Nasdaq: INZY) (“Inozyme” or the “Company”), a clinical-stage rare disease biopharmaceutical company developing novel therapeutics ...

Collaboration aims to accelerate the development of treatments for chronic kidney disease (CKD) and other conditions Rectify has developed oral, small molecules that can potentially reduce ...

Yabing Chen, Ph.D., the Jay M. McDonald Endowed Chair in Laboratory Medicine and Vice Chair of Faculty Development and Education, has received two R01 awards amounting to more than $5 million to ...

RTY-822 treatment led to statistically significant reductions in vascular calcification in the aorta and the femoral arteries After a six-week treatment course, RTY-822 improved glomerular and tubular ...