Pregnenolone is a precursor of neuroactive steroids that is thought to have no physiological activity itself. However, a new study shows that pregnenolone is strongly upregulated by Δ ...

Pregnenolone is a hormone with an important role in producing many other hormones, like testosterone and progesterone, according to the National Institutes of Health (NIH). Your body generally makes ...

Emerging evidence suggests that the pathogenesis of depressive disorders (DDs) is associated with neuronal abnormalities in brain microtubule function, including changes in a-tubulin isoforms.

Researchers may have found a hormonal way to block pot smokers from getting high. They say the findings could someday lead to new treatments for addiction. A study published in Science on Jan. 3 shows ...

Leave it to science to find a way to harsh the mellow of marijuana. A French research team has discovered a natural chemical brake that can tamp down the effects of THC, the main intoxicant in ...

PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...