High-resolution structures of nascent polypeptide chains in complex with the ribosome — the cell’s protein-synthesis machinery — reveal how the ribosome guides protein folding. Ribosomal attachment ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

For those outside the chemistry cognoscenti, the announcement might have seemed little more than researchers patting each other on the back. But the question of protein folding had plagued scientists ...

In order to fulfil their many functions, proteins must be folded into the correct shape. Researchers at the University of Basel have now discovered tiny “folding factories” in cells that enable ...