A new study found that a single mutation to the hemagglutinin protein of an H5N1 virus isolated from a dairy worker in Texas this spring switched the protein’s binding specificity from avian- to human ...

When a highly pathogenic strain of H5N1 influenza virus emerged in US dairy cattle in March, scientists around the world had a slew of questions about the virus’s characteristics. In a new paper ...

Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets. After earning ...

The ability to grow stem cell-derived biological tissues, such as skin and other organs, in the laboratory holds promise for applications in areas including wound healing and transplants. However, ...

A new editorial paper was published in Oncoscience, titled "PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors; PARs." While targeted cancer therapy is greatly ...

"To provide direct evidence for binding of the molecule at different pockets of the receptor, we have developed a new assay, which enables us to measure the binding specifically at the extracellular ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other immune responses. However, histamine is also a major neurotransmitter in the ...

A new study reveals a critical vulnerability in a brain receptor targeted by a rare autoimmune disease. Researchers have ...

Of the 20,000+ human genes, none has greater influence on late-onset Alzheimer’s disease than APOE. But why do certain variants of this lipid transporter protect the brain, while others endanger it? A ...

Psychedelics, psychoactive substances that alter people's perceptions, mood and thought patterns, have recently shown promise ...