The immune system regulates homeostasis by attacking foreign bacteria, viruses, and other infections. Different immune cells are generated for specific functions to fight off disease and to maintain ...
The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury or partial resection. A study led by researchers at the University of ...
A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, according to a recent study published in ...
Explore the role of transcription factor biology in drug discovery and how it impacts our understanding of disease mechanisms ...
Researchers identified DMTF1 as a key transcription factor driving neural stem cell regeneration during aging. The study ...
Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have found that a key ...
Scientists have generated a comprehensive map of the gene targets regulated by the transcription factors HNF4A and HNF1A in human pancreatic beta cells and liver cells. Published in the journal Nature ...
Bioengineers have developed a generalizable method to address 'off-target' binding, a significant problem in the field of synthetic biology. Taking a cue from nature, the researchers showed they could ...
Scientists at St. Jude Children's Research Hospital have reconciled two closely related but contentious mechanisms underlying transcription, the process of converting genetic information in DNA into ...